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By picking out very low-sodium XYWAV about XYREM® (sodium oxybate) oral Remedy, a significant sodium oxybate, you are able to handle your cataplexy and/or excessive daytime sleepiness in narcolepsy although also lessening your cardiovascular danger as a result of abnormal sodium ingestion.
These situations occurred in patients with and devoid of preceding histories of depressive Ailments. The emergence of melancholy in people taken care of with XYWAV requires careful and immediate analysis. Observe clients for that emergence of enhanced depressive signs and/or suicidality although having XYWAV.
Convey to your doctor if you or your son or daughter have or experienced melancholy or have tried to hurt on your own or by themselves. Get in touch with your physician right away When you've got or your son or daughter has signs of psychological health conditions or possibly a modify in excess weight or hunger.
As a result of hazards of central nervous process depression and abuse and misuse, XYWAV is out there only by way of a restricted distribution plan known as the XYWAV and XYREM REMS.
The overall adverse reaction profile of XYREM during the pediatric clinical trial was just like that seen inside the adult scientific demo system. The protection profile in pediatric individuals with XYWAV is anticipated being similar to that of Grownup people treated with XYWAV and also to that of pediatric clients addressed with XYREM.
Having an informed discussion—which includes referring to sodium ingestion—is crucial for people with narcolepsy
I used to be anxious about starting a whole new cure; how it could fit in my agenda, what probable side effects I might have, irrespective of whether I'd personally manage to acquire it given that I used to be even now taking a stimulant, and just the pressure of a different medication. But I am so delighted I talked as a result of my concerns with my physician and decided to go ahead and take leap.”
That's a little something to recall for individuals with narcolepsy who are now two.5x a lot more likely* to possess a stroke† and one.6x far more possible* to have a coronary heart assault.†
As you might know, sodium ingestion is really a modifiable hazard element for heart problems. With 131 mg of sodium per utmost suggested nine g nightly dose, XYWAV is a lower-sodium oxybate treatment.
Because of these hazards, It's important to go with the XYWAV and XYREM REMS to obtain your or your child's prescription for XYWAV loaded.
Irresistible urge to snooze Recurrent tiredness Hassle being awake and alert during the day
Because the signs and symptoms can be complicated to recognize, folks residing with narcolepsy might end up looking at numerous doctors in excess of quite a few decades before acquiring a prognosis
For those who have been diagnosed with narcolepsy and remain having difficulties to remain awake during the day, discuss with your doctor
A big increase in the amount of central apneas and clinically sizeable oxygen desaturation could come about in patients with obstructive rest apnea addressed with XYWAV. Prescribers ought to be mindful that rest-similar respiratory Conditions are usually more common in obese sufferers, in Males, in postmenopausal Females not on hormone substitution therapy, and amongst people with narcolepsy.
The emergence or rise in the event of behavioral or psychiatric activities in individuals taking XYWAV should be diligently monitored.
XYWAV may perhaps impair respiratory push, read more particularly in sufferers with compromised respiratory perform. In overdoses of oxybate and with illicit use of GHB, everyday living-threatening respiratory despair has become documented. Improved apnea and decreased oxygenation could manifest with XYWAV administration in adult and pediatric people.